NexImmune is a rapidly growing leader in the emerging field of antigen-directed immunotherapies. We are developing a novel technology that uses natural biology to orchestrate a targeted cell-mediated immune response across a broad range of diseases. We can customize our technology to “intensify” a targeted immune response to treat cancer or infectious disease. Conversely, we can also customize it to “dampen” an overactive immune response to treat autoimmune disorders.
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T cells are the “foot soldiers” of the immune system.
Their role is to identify, engage, and destroy diseased cells within our bodies. Each T cell requires a specific set of instructions, otherwise the T cell is incapable of performing its critical immune function. These instructions are provided through very specific signaling proteins and are normally delivered to the T cell by dendritic cells. In many diseases, the dendritic cell becomes dysfunctional and is no longer able to direct healthy T cell function, and ultimately the immune system breaks down.
NexImmune “AIMs” to orchestrate cell-mediated immune responses across a range of diseases.
With an urgent drive and singular focus on meeting the needs of waiting patients, our team is executing a bold strategy to deliver immunotherapies that go beyond incremental improvements to those with curative potential.
The foundation of our unique approach focuses on modulating the role that T cells play within the immune system. Our proprietary nanotechnology platform, Artificial Immune Modulation (AIM), employs natural biology to direct specific T cell-mediated immune responses capable of treating a variety of diseases.
The AIM nanoparticles use biology similar to that of healthy dendritic cells to deliver the instructions necessary to direct healthy T cell function. Each AIM nanoparticle can be programmed to deliver customized instructions directly to specific populations of T cells, bringing pharmaceutical precision to cell therapy.